Increased Serum Levels of IFN-γ, IL-1β, and IL-6 in Patients with Alopecia Areata and Nonsegmental Vitiligo
Table 3
The correlation between serum levels of interferon γ (IFN-γ), interleukin- (IL-) 1β, and IL-6 (pg/ml) and extent, activity, and duration of the disease among patients with alopecia areata (AA) and patients with nonsegmental vitiligo (NSV).
Correlation between serum cytokine levels and
Alopecia areata (AA)
Nonsegmental vitiligo (NSV)
Extent of AA (SALT)
Activity of AA (VIDA)
Duration of AA
Extent of NSV (VASI)
Activity of NSV (VIDA)
Duration of NSV
IFN-γ (q in the Spearman test/ value)
-0.055/0.759218
-0.206/0.250208
-0.150/0.421353
-0.055/0.778851
-0.148/0.444011
-0.137/0.478715
IL-1β ( in the Spearman test/ value)
0.038/0.833562
0.181/0.314325
-0.073/0.694889
0.383/0.040441
-0.435/0.018387
0.458/0.012573
IL-6 ( in trhe Spearman test/ value)
0.116/0.520565
-0.050/0.784260
0.453/0.010474
-0.054/0.779845
-0,190/0.323085
0,222/0,247687
SALT: Severity of Alopecia Tool score; VIDA: Vitiligo Disease Activity Score; VASI: Vitiligo Area Severity Index; IL: interleukin; IFN: interferon.