Clinical Study

The Beneficial Effects of Alpha Lipoic Acid Supplementation on Lp-PLA2 Mass and Its Distribution between HDL and apoB-Containing Lipoproteins in Type 2 Diabetic Patients: A Randomized, Double-Blind, Placebo-Controlled Trial

Table 1

Baseline characteristics of participants.

VariableALA group ()Placebo group () value

Age (year)a52.66 (4.81)53.34 (4.45)0.53
Female/maleb20 (57.1)/15 (42.9)19 (54.3)/16 (45.7)0.81
Menopause b13 (37.1)14 (40)0.81
Duration of diabetes (year)a3.65 (1.67)3.57 (1.83)0.83
HbA1Ca6.6 (0.38)6.7 (0.21)0.17
BMIa25.4 (1.25)24.93 (1.26)0.11
Medicationb
 Metformin32 (91.4)31 (88.6)0.69
 Sulfonylurea8 (22.9)10 (28.6)0.58
 ARB28 (80)27 (77.1)0.77
 ACEI4 (11.4)5(14.3)0.72
 Statins29 (82.9)30 (85.7)0.74
 Aspirin29 (82.9)27 (77.1)0.55
Physical activity levelb
 Low20 (57.1)21 (60)0.80
 Moderate15 (42.9)14 (40)

aPresented as mean (SD), values are resulted from independent sample t-test. bPresented as number (%), values are resulted from a chi-square test. Low physical activity: score less than 600 MET-minutes/week and moderate physical activity: score between 600 and 3000 MET-minutes/week.