Hypoxia Helps Maintain Nucleus Pulposus Homeostasis by Balancing Autophagy and Apoptosis

<div>Morphometric and protein expression analyses of an <i>ex vivo</i> rat IVD culture model. (a) Representative histological images of <i>ex vivo</i> IVD cultures from 5-week-old and 10-week-old rats with or without injury (injection of 10 <i>μ</i>L of PBS into the disc). Images shown are at 40x (H&amp;E), 200x (H&amp;E and Safranin O), and 400x (IHC) magnification. The dotted line indicates the NP. (b) Representative immunoblotting images (left) and statistical analysis of protein levels in the experimental groups. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Hypoxia Helps Maintain Nucleus Pulposus Homeostasis by Balancing Autophagy and Apoptosis 