Comparative Transcriptome Analysis Reveals the Protective Mechanism of Glycyrrhinic Acid for Deoxynivalenol-Induced Inflammation and Apoptosis in IPEC-J2 Cells

Figure 6

Protein-protein interaction (PPI) network construction of DEGs. (a) The PPI network of DEGs identified from CON vs. DON. (b) The top 30 highly connected DEGs with 19 edges of the PPI network and the top 2 significant modules extracted from the PPI network (MCODE scores are 15 and 13). (c) PPI network constructed from 79 coexpressed genes between CON vs. DON and DON vs. GAD. Red represents gene expression upregulated, and blue represents gene expression downregulated in (a) and (b). Node size indicates the number of genes interacted in (a) and (c). Line thickness indicates the strength of data support in (c). The interaction score was set to 0.9 in (a) and (b) and 0.4 for (c).

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