Comparative Transcriptome Analysis Reveals the Protective Mechanism of Glycyrrhinic Acid for Deoxynivalenol-Induced Inflammation and Apoptosis in IPEC-J2 Cells

Table 1

The summary of 63 coexpressed DEGs in CON vs. DON and DON vs. GAD.

Gene ID	Gene name	Full names of genes	CON vs. DON	CON vs. GA	CON vs. GAD	DON vs. GAD
ENSSSCG00000029311	MYPN	Myopalladin	Up	Down	—	Down
ENSSSCG00000006051	CTHRC1	Collagen triple helix repeat containing 1	Up	Down	Down	Down
ENSSSCG00000011972	FILIP1L	Filamin A interacting protein 1 like	Up	Down	—	Down
ENSSSCG00000008648	RSAD2	Radical S-adenosyl methionine domain containing 2	Up	Down	Down	Down
ENSSSCG00000035420	HES4	Hes family bHLH transcription factor 4	Up	Down	Down	Down
ENSSSCG00000029849	S1PR1	Sphingosine-1-phosphate receptor 1	Up	—	—	Down
ENSSSCG00000040359	GOLGA7B	Golgin A7 family member B	Up	—	Up	Down
ENSSSCG00000009789	HCAR1	Hydroxycarboxylic acid receptor 1	Up	—	—	Down
ENSSSCG00000025245	ARMC5	Armadillo repeat containing 5	Up	—	—	Down
ENSSSCG00000025134	FAM171B	Family with sequence similarity 171 member B	Up	—	Down	Down
ENSSSCG00000040575	ISG15	ISG15 ubiquitin-like modifier	Up	—	—	Down
ENSSSCG00000009051	IL-15	Interleukin 15	Up	—	—	Down
ENSSSCG00000017705	CCL5	C-C motif chemokine ligand 5	Up	—	—	Down
ENSSSCG00000021944	RAC2	Rac family small GTPase 2	Up	—	—	Down
ENSSSCG00000011195	GALNT15	Polypeptide N-acetylgalactosaminyltransferase 15	Up	—	Up	Down
ENSSSCG00000024158	ANO1	Anoctamin 1	Up	—	—	Down
ENSSSCG00000021027	PGBD5	PiggyBac transposable element-derived 5	Up	—	—	Down
ENSSSCG00000027911	LTB4R	Leukotriene B4 receptor	Up	—	—	Down
ENSSSCG00000009100	TNIP3	TNFAIP3-interacting protein 3	Up	—	Up	Down
ENSSSCG00000017277	PECAM1	Platelet and endothelial cell adhesion molecule 1	Up	—	Up	Down
ENSSSCG00000034870	—	—	Up	—	—	Down
ENSSSCG00000033093	RGS6	Regulator of G protein signaling 6	Up	—	—	Down
ENSSSCG00000026890	GALNT6	Polypeptide N-acetylgalactosaminyltransferase 6	Up	—	—	Down
ENSSSCG00000031262	TXNIP	Thioredoxin-interacting protein	Up	—	Up	Down
ENSSSCG00000003080	—	—	Up	—	—	Down
ENSSSCG00000001916	INSYN1	Inhibitory synaptic factor 1	Up	—	—	Down
ENSSSCG00000029438	SESN2	Sestrin 2	Down	Up	—	Up
ENSSSCG00000035895	JDP2	Jun dimerization protein 2	Down	Up	—	Up
ENSSSCG00000039761	MYCL	MYCL protooncogene, bHLH transcription factor	Down	Up	—	Up
ENSSSCG00000022649	SLC7A11	Solute carrier family 7 member 11	Down	Up	—	Up
ENSSSCG00000038521	CHAC1	ChaC glutathione-specific gamma-glutamylcyclotransferase 1	Down	Up	—	Up
ENSSSCG00000021232	SYNC	Syncoilin, intermediate filament protein	Down	Up	—	Up
ENSSSCG00000023749	—	—	Down	Up	—	Up
ENSSSCG00000008153	SLC9A2	Solute carrier family 9 member A2	Down	—	—	Up
ENSSSCG00000033059	CASKIN1	CASK-interacting protein 1	Down	—	Down	Up
ENSSSCG00000002778	ZDHHC1	Zinc finger DHHC-type containing 1	Down	—	—	Up
ENSSSCG00000016873	NIM1K	NIM1 serine/threonine protein kinase	Down	—	Down	Up
ENSSSCG00000011293	POMGNT2	Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)	Down	—	—	Up
ENSSSCG00000007486	CYP24A1	Cytochrome P450, family 24, subfamily A, polypeptide 1	Down	—	Down	Up
ENSSSCG00000029662	RASSF4	Ras association domain family member 4	Down	—	—	Up
ENSSSCG00000003848	LRP8	LDL receptor-related protein 8	Down	—	Down	Up
ENSSSCG00000025992	ENPP3	Ectonucleotide pyrophosphatase/phosphodiesterase 3	Down	—	—	Up
ENSSSCG00000027877	TLR10	Toll-like receptor 10	Down	—	—	Up
ENSSSCG00000016562	SSMEM1	Serine-rich single-pass membrane protein 1	Down	—	—	Up
ENSSSCG00000038026	RAB12	RAB12, member RAS oncogene family	Down	—	—	Up
ENSSSCG00000034863	PARD6A	Par-6 family cell polarity regulator alpha	Down	—	Down	Up
ENSSSCG00000011330	NBEAL2	Neurobeachin-like 2	Down	—	Down	Up
ENSSSCG00000011949	CEP97	Centrosomal protein 97	Down	—	—	Up
ENSSSCG00000014437	PPARGC1B	PPARG coactivator 1 beta	Down	—	—	Up
ENSSSCG00000035969	THRA	Thyroid hormone receptor alpha	Down	—	—	Up
ENSSSCG00000036172	SP9	Sp9 transcription factor	Down	—	Down	Up
ENSSSCG00000035876	ZNF599	Zinc finger protein 599	Down	—	—	Up
ENSSSCG00000024759	—	—	Down	—	—	Up
ENSSSCG00000011915	GRAMD1C	GRAM domain containing 1C	Down	—	—	Up
ENSSSCG00000026849	CCNO	Cyclin O	Down	—	—	Up
ENSSSCG00000003423	DRAXIN	Dorsal inhibitory axon guidance protein	Down	—	—	Up
ENSSSCG00000008227	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Down	—	—	Up
ENSSSCG00000031321	NR4A1	Nuclear receptor subfamily 4 group A member 1	Down	—	—	Up
ENSSSCG00000008413	GPR75	G protein-coupled receptor 75	Down	—	—	Up
ENSSSCG00000005673	IER5L	Immediate early response 5 like	Down	—	—	Up
ENSSSCG00000016420	INSIG1	Insulin-induced gene 1	Down	—	Down	Up
ENSSSCG00000037391	—	—	Down	—	—	Up
ENSSSCG00000007491	MC3R	Melanocortin 3 receptor	Down	—	—	Up

Note: CON: control group; DON: the single DON (0.5 μg/mL) group; GA: the single GA (400 μg/mL) group; GAD: 400 μg/mL GA+0.5 μg/mL DON group.