Research Article

Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

Figure 6

Immunohistochemical analysis of the expression of p-Akt in all groups. (a) Sham group. (b) Intestinal ischemia/reperfusion (I/R) group. (c) Dexmedetomidine-treated I/R (DEX) group. (d) Dexmedetomidine- and AM630-treated I/R (DA) group. (e) AM630-treated I/R (AI) group. (f) Dexmedetomidine- and wortmannin-treated I/R (DW) group. (g) Wortmannin-treated I/R (WI) group (original magnification, ×400). (h) Integrated optical density (IOD) of p-Akt expression in all groups. Data are expressed as , rats per group. versus the Sham group, # versus the I/R group, & versus the DEX group.
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