Interplay between Oxidative Stress, Inflammation, and Amyloidosis in the Anterior Segment of the Eye; Its Pathological Implications

Figure 1

Schematic representation of the oxidative-inflammatory-amyloidogenic negative feedback that occurs in the anterior segment of the eye. The eye is one of the major targets of the OS attack, inflammation, and amyloidogenic processes due to exposition on several environmental factors that contributes to the development and progression of ocular diseases, such as glaucoma, dry eye syndrome, keratitis, and cataracts among other pathologies. The three main factors are involved in a vicious circle that we called “oxidative-inflammatory-amyloidogenic negative feedback.”