Ceftriaxone Calcium Crystals Induce Acute Kidney Injury by NLRP3-Mediated Inflammation and Oxidative Stress Injury
Rats administered with high concentration of ceftriaxone and calcium developed crystal nephropathy and inflammation. (a, b) Representative von Kossa staining of kidney sections ((a) NC group; (b) group 1, μm). (c, d) TEM images of extracellular (c) and intracellular (d) crystal precipitates. (e, f) F4/80 staining for macrophages/monocytes of kidney sections ((e) NC group; (f) group 1, μm).
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