RiPerC Attenuates Cerebral Ischemia Injury through Regulation of miR-98/PIK3IP1/PI3K/AKT Signaling Pathway

Figure 3

The miRNA-98 expression in hippocampus tissue plays a key role in cerebral ischemic injury. (a) Representative images of TTC staining in brain sections collected from rat receiving RiPerC operation or ICV injection at 1 day after reperfusion. (b) The neurological deficit score was assessed by the Longa scale scoring system at 1 day after reperfusion. (c) Quantitative data regarding the effects of the RiPerC operation on cerebral infarction as assessed by TTC histology at 1 day ( per group). (d, e) The expression of PI3KIP1 and miR-98 in hippocampus detected by qPCR. (f–h) The expression of IL-1β, IL-6, and TNF-α in rat serum by ELISA.

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