Andrographolide Exerts Antihyperglycemic Effect through Strengthening Intestinal Barrier Function and Increasing Microbial Composition of <i>Akkermansia muciniphila</i>

<div>Andrographolide modulated gut microbiota composition. (a) Observed species, (b) Chao, (c) Ace, (d) Shannon’s diversity, and (e) Simpson’s diversity were obtained by analyzing 16S rDNA sequencing. (f) Statistical comparisons of gut bacterial profiles at the phylum level. (g, h) The Bacteroidetes/Firmicutes ratio was calculated. Control: db/db mice administered with vehicle; AG: db/db mice administered with 150 mg/kg andrographolide. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Andrographolide Exerts Antihyperglycemic Effect through Strengthening Intestinal Barrier Function and Increasing Microbial Composition of <i>Akkermansia muciniphila</i> 

Figure 6 | Andrographolide Exerts Antihyperglycemic Effect through Strengthening Intestinal Barrier Function and Increasing Microbial Composition of Akkermansia muciniphila 