Salivary Gland Dysfunction in Stroke Patients Is Associated with Increased Protein Glycoxidation and Nitrosative Stress

Table 3

Comparison between NWS and SWS in healthy controls and stroke patients.

Parameter	Control			Stroke NS			Stroke HP
	NWS	SWS	value	NWS	SWS	value	NWS	SWS	value
Amadori products (μmol/mg protein)			0.16			0.01			<0.0001
AGE (AFU/mg protein)			0.004			0.88			0.47
PC (nmol/mg protein)			0.13			0.06			0.04
Thiol groups (μg/mg protein)			<0.0001			0.0002			0.0002
Dityrosine (AFU/mg protein)			<0.0001			0.03			<0.0001
Kynurenine (AFU/mg protein)			0.093			0.56			0.39
N-formylkynurenine (AFU/mg protein)			0.001			0.002			0.002
Tryptophan (AFU/mg protein)			0.55			0.002			0.39
NO (ng/mg protein)			0.004			0.005			0.89
Peroxynitrite (nmol/mg protein)			<0.0001			<0.0001			<0.0001
Nitrotyrosine (pmol/mg protein)			<0.0001			0.18			0.002

Abbreviations: NS: normal salivary secretion; HP: reduced salivary secretion; NWS: nonstimulated whole saliva; SWS: stimulated whole saliva; AGE: advanced glycation end products; PC: protein carbonyls; NO: nitric oxide.