Salivary Gland Dysfunction in Stroke Patients Is Associated with Increased Protein Glycoxidation and Nitrosative Stress

Table 4

Correlations between clinical parameters, redox biomarkers, and salivary flow rate in healthy controls and stroke patients.

Parameter	Control				Stroke
	value	value			value		value
	NWS flow	SWS flow	NWS flow	SWS flow	NWS flow	SWS flow	NWS flow	SWS flow
Amadori products	0.197	-0.169	0.297	0.372	-0.875	0.084	<0.0001	0.658
AGE	0.255	0.03	0.174	0.873	-0.768	-0.283	<0.0001	0.13
PC	0.055	-0.394	0.772	0.031	-0.451	-0.268	0.012	0.153
Thiol groups	0.014	0.161	0.943	0.395	0.533	0.369	0.002	0.045
Dityrosine	-0.269	0.044	0.15	0.816	-0.706	-0.401	<0.0001	0.028
Kynurenine	0.096	0.353	0.613	0.055	-0.392	0.207	0.032	0.272
N-formylkynurenine	0.178	-0.167	0.348	0.378	-0.585	-0.484	0.001	0.007
Tryptophan	0.03	-0.102	0.876	0.592	0.291	0.155	0.119	0.414
NO	-0.344	-0.047	0.063	0.806	0.665	0.004	<0.0001	0.985
Peroxynitrite	-0.133	0.222	0.484	0.238	-0.102	0.025	0.592	0.898
Nitrotyrosine	0.028	-0.013	0.884	0.945	-0.682	0.072	<0.0001	0.706

Abbreviations: NS: normal salivary secretion; HP: reduced salivary secretion; NWS: nonstimulated whole saliva; SWS: stimulated whole saliva; AGE: advanced glycation end products; PC: protein carbonyls; NO: nitric oxide.