Oxidative Stress in Ischemic Heart Disease

Figure 4

Difference between coronary microvascular dysfunction and atherothrombotic coronary artery disease. ET-1: endothelin -1; PGH2: prostaglandin H2; TXA2: thromboxane A2; ROS: reactive oxygen species; NO: nitric oxide; EDHF: endothelium-derived hyperpolarizing factor; LDL: low-density lipoprotein; TNF-α: tumor necrosis factor – α; IL-1: interleukin-1; IFN- γ:), interferon-gamma; VSMC: vascular smooth muscle cells; EC: endothelial cell.