Sustained Release of Melatonin from GelMA Liposomes Reduced Osteoblast Apoptosis and Improved Implant Osseointegration in Osteoporosis

Figure 1

In vitro characterization of GelMA-DOPA@MT. (a) In vitro drug release behavior. (b) Swelling of GelMA with different modifications. (c) GelMA-DOPA at different concentrations. (d) Degradation of GelMA with different modifications. (e) GelMA-DOPA at different concentrations. (f, g) Compressive testing of GelMA with different modifications and Young’s modulus. (h, i) Compressive testing on GelMA-DOPA at different concentrations and Young’s modulus. (j, k) Investigation of the adhesive properties of GelMA-DOPA at different concentrations and Young’s modulus. (l) Cytotoxicity of GelMA derivatives. ( per group, , , ).

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