Research Article
Mitochondrial and Peroxisomal Alterations Contribute to Energy Dysmetabolism in Riboflavin Transporter Deficiency
Figure 5
Confocal analysis of MTCO2 (Mito) in Ctrl and RTD cells: (a) immunofluorescence images of the mitochondrial marker (in green) demonstrating the higher abundance of organelles in patients’ cells, as compared to controls. White arrowheads, immunoreactive aggregates; (b) fluorescence intensity levels reveal a significant increase () of α-mitochondria in RTD cells vs. Ctrl iPSCs. Nuclei are stained with Hoechst (in blue).
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