Oxidative Medicine and Cellular Longevity / 2020 / Article / Fig 4

Research Article

A Novel Molecular Mechanism of IKKε-Mediated Akt/mTOR Inhibition in the Cardiomyocyte Autophagy after Myocardial Infarction

Figure 4

Knockdown of IKKε promotes starvation-induced autophagy in H9c2 cells. (a, b) Representative western blots and quantitative results of IKKε, LC3I/II, ATG-5, C-caspase 3, Bcl-2, and Bax in H9c2 cells ( for each group). ; ; . (c) Representative immunofluorescent staining of LC3 in H9c2 cells ( for each group; magnification, 600x). Scale bar represents 10 μm. (d) The quantification of autophagy is expressed as the number of LC3 puncta per area ( for each group). .

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