Protective Effect of Polydatin on Jejunal Mucosal Integrity, Redox Status, Inflammatory Response, and Mitochondrial Function in Intrauterine Growth-Retarded Weanling Piglets

Figure 5

Effect of dietary polydatin supplementation on the protein expression of jejunal total AMPKα (b), phosphorylated AMPKα (c), SIRT1 (e), and PGC-1α (f) and the relative phosphorylation of AMPKα (d) in weanling piglets with different birth weights. Data are presented as the means and SEM, . . Different letters above the bar indicate a significant difference (). ACTB: beta actin; CON: basal diet; IUGR: intrauterine growth retardation; mtDNA: mitochondrial DNA; NBW: normal birth weight; p-AMPKα: phosphorylated adenosine monophosphate-activated protein kinase alpha; PD: polydatin-supplemented diet; PGC-1α: peroxisome proliferation-activated receptor gamma coactivator 1 alpha; SIRT1: sirtuin 1; t-AMPKα: total adenosine monophosphate-activated protein kinase alpha.

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