Protective Effect of Polydatin on Jejunal Mucosal Integrity, Redox Status, Inflammatory Response, and Mitochondrial Function in Intrauterine Growth-Retarded Weanling Piglets

Table 4

Effect of dietary polydatin supplementation on the mRNA levels of jejunal tight junction complexes in weanling piglets with different birth weights.

Items^1,2	CON		PD		SEM	value
	NBW	IUGR	NBW	IUGR		BW	Diet
ZO1	1.00^ab	0.68^b	1.03^a	0.96^ab	0.06	0.090	0.171	0.279
OCLN	1.00^b	0.54^c	1.53^a	0.91^bc	0.10	0.001	0.004	0.579
CLDN1	1.00	1.13	1.04	0.59	0.11	0.456	0.259	0.187
CLDN2	1.00^b	1.60^a	1.26^ab	0.91^b	0.10	0.489	0.233	0.013
CLDN3	1.00	1.09	1.30	1.11	0.11	0.839	0.486	0.550

¹Data are presented as the means and SEM, . Mean values with different letters indicate a significant difference (). ²BW: birth weight; : the interaction effect of the main effects (BW and diet); CLDN1: claudin 1; CLDN2: claudin 2; CLDN3: claudin 3; CON: basal diet; IUGR: intrauterine growth retardation; NBW: normal birth weight; OCLN: occludin; PD: polydatin-supplemented diet; ZO1: zonula occludens 1.