Research Article

Protective Effect of Polydatin on Jejunal Mucosal Integrity, Redox Status, Inflammatory Response, and Mitochondrial Function in Intrauterine Growth-Retarded Weanling Piglets

Table 7

Effect of dietary polydatin supplementation on the jejunal redox status of weanling piglets with different birth weights.

Items1,2CONPDSEM value
NBWIUGRNBWIUGRBWDiet

SOD (U/mg protein)62.85ab52.99b70.58a68.13a2.620.2100.0260.445
GSH-Px (U/mg protein)60.9757.8265.9551.203.180.1770.8990.376
CAT (U/mg protein)7.778.148.396.870.260.2670.5260.075
GST (U/mg protein)79.92ab70.71b97.09a97.48a4.080.5410.0060.506
GR (U/g protein)42.2737.5945.8040.361.690.1490.3610.911
GSH (μmol/mg wet weight)0.45a0.31b0.47a0.38ab0.020.0010.1050.384
MDA (nmol/mg protein)0.57b0.90a0.60b0.56b0.040.0230.0150.006
8-OHDG (ng/mg DNA)0.85b1.35a0.75b0.89b0.070.0170.0340.158

1Data are presented as the means and SEM, . Mean values with different letters indicate a significant difference (). 2BW: birth weight; : the interaction effect of the main effects (BW and diet); CAT: catalase; CON: basal diet; GSH: reduced glutathione; GSH-Px: glutathione peroxidase; GR: glutathione reductase; GST: glutathione S-transferase; IUGR: intrauterine growth retardation; MDA: malondialdehyde; NBW: normal birth weight; 8-OHDG: 8-hydroxy-2-deoxyguanosine; PD: polydatin-supplemented diet; SOD: superoxide dismutase.