Caffeic Acid Phenethyl Ester Protects against Experimental Autoimmune Encephalomyelitis by Regulating T Cell Activities

Figure 2

Effects of CAPE on lymphocyte proliferation and CD4⁺ T cell expression. Cells were cultured at a concentration of cells/ml per well in 96-well plates. To induce lymphocyte proliferation, cells were stimulated with ConA (5 μg/ml) or LPS (1 μg/ml) for 48 h. Cell viability among the groups treated with various concentrations of CAPE (0-20 μM) (a). Cell proliferation of ConA- (b) and LPS-stimulated (c) lymphocytes. The percentage of CD4⁺ T cells in ConA-stimulated splenocytes (d). The data () represent three independent experiments. , , versus the vehicle group.

(a)

(b)

(c)

(d)