Research Article

Neuroprotective Effect of the Inhibitor Salubrinal after Cardiac Arrest in a Rodent Model

Table 1

Physiological variables at baseline, 30 min after ROSC, and 10 min after MV weaning. Comparisons of the results of arterial blood gas analysis, HR, and MAP revealed no difference between the vehicle group and the Sal group by Student’s -test.

Sham ()Vehicle ()Sal () value

Before CA
 Body weight (g)0.76
 pH0.99
 PaCO2 (mmHg)0.95
 PaO2 (mmHg)0.39
 Lactate (mmol L-1)0.92
 Base excess0.28
 Mean arterial pressure (mmHg)0.47
 Heart rate (bpm)0.24
 Body temperature0.32
30 min after ROSC
 pHN/A0.74
 PaCO2 (mmHg)N/A0.67
 PaO2 (mmHg)N/A0.56
 Lactate (mmol L-1)N/A0.53
 Base excessN/A0.92
 Mean arterial pressure (mmHg)N/A0.93
 Heart rate (bpm)N/A0.84
 Body temperatureN/A0.74
10 min after weaning of MV
 pHN/A0.80
 PaCO2 (mmHg)N/A0.91
 PaO2 (mmHg)N/A0.35
 Lactate (mmol L-1)N/A0.34
 Base excessN/A0.97
 Mean arterial pressure (mmHg)N/A0.75
 Heart rate (bpm)N/A0.47
 Body temperatureN/A0.55