Oleanolic Acid Decreases IL-1<i>β</i>-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-<i>κ</i>B Axis in Osteoarthritis

<div>The effects of SIRT3 and OLA on IL-1<i>β</i>-induced intracellular levels of ROS in human FLS. FLS were pretreated with SIRT3-OE or SIRT3-KD and then incubated with or without IL-1<i>β</i> (10 ng/ml) for 24 h. The ROS were measured and viewed using a fluorescence microscope, and the quantitative analysis is listed. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Oleanolic Acid Decreases IL-1<i>β</i>-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-<i>κ</i>B Axis in Osteoarthritis 

Oxidative Medicine and Cellular Longevity

Oleanolic Acid Decreases IL-1β-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-κB Axis in Osteoarthritis

Figure 3