Paricalcitol Attenuates Contrast-Induced Acute Kidney Injury by Regulating Mitophagy and Senescence

<div>Effect of paricalcitol on biochemical tests and histological injuries in the kidney after ioversol administration. (a) Serum BUN and creatinine levels at 12 hours and (b) PAS staining in the kidney after ioversol administration. The injury score was determined as described in Materials and Methods. Images are representative of each group. Con: PBS-treated group; PC: paricalcitol-treated group; CONT: ioversol-treated group; PC+CONT: paricalcitol- and ioversol-treated group. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Paricalcitol Attenuates Contrast-Induced Acute Kidney Injury by Regulating Mitophagy and Senescence 