Prooxidation and Cytotoxicity of Selenium Nanoparticles at Nonlethal Level in Sprague-Dawley Rats and Buffalo Rat Liver Cells

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Gene</td><td class="align_center">Forward sequences</td><td class="align_center">Reverse sequences</td><td class="align_center">GenBank accession # of mRNAs</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">GPX1</td><td class="align_center">AGTCCACCGTGTATGCCTTCTCC</td><td class="align_center">TCTCTTCATTCTTGCCATTCTCCTG</td><td class="align_center">NM_030826</td></tr><tr><td class="align_left">GPX4</td><td class="align_center">GGAGGCAGGAGCCAGGAAGTAA</td><td class="align_center">AGCCGTTCTTATCAATGAGAAACTTGG</td><td class="align_center">NM_001039849</td></tr><tr><td class="align_left"><i>β</i>-Actin</td><td class="align_center">CGTTGACATCCGTAAAGACCTC</td><td class="align_center">TAGGAGCCAGGGCAGTAATCT</td><td class="align_center">NM_031144</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>GPX1: glutathione peroxidase 1; GPX4: glutathione peroxidase 4. <i>β</i>-Actin was used as an internal control to normalize target gene levels.<br/></div></td></tr></table>

<div>Sequences of primers designed for RT-qPCR.</div>

Oxidative Medicine and Cellular Longevity

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Table 1

Table 1: Prooxidation and Cytotoxicity of Selenium Nanoparticles at Nonlethal Level in Sprague-Dawley Rats and Buffalo Rat Liver Cells 