Research Article

Cornelian Cherry Iridoid-Polyphenolic Extract Improves Mucosal Epithelial Barrier Integrity in Rat Experimental Colitis and Exerts Antimicrobial and Antiadhesive Activities In Vitro

Table 5

The impact of cornelian cherry iridoid-polyphenolic extract and loganic acid on IL-23, IL-17, TNF-α, and chemerin concentrations in colon tissues in experimental groups. Control = control group; TNBS = group receiving only TNBS; CE20, CE100 = groups receiving 20 or 100 mg/kg cornelian cherry extract with TNBS, respectively; LA10, LA50 = groups receiving 10 or 50 mg/kg loganic acid with TNBS, respectively; SA = group receiving 100 mg/kg sulfasalazine with TNBS; CE20+SA, CE100+SA = groups receiving 20 or 100 mg/kg cornelian cherry extract and 100 mg/kg sulfasalazine with TNBS, respectively; and LA10+SA, LA50+SA = groups receiving 10 or 50 mg/kg loganic acid and 100 mg/kg sulfasalazine with TNBS, respectively. Data are presented as . Differences ^^ vs. the control group; ^^^ vs. the control group; vs. the TNBS group; vs. the TNBS group; vs. the TNBS group; # vs. the sulfasalazine group; and ## vs. the sulfasalazine group were deemed statistically significant.

GroupIL-23 (pg/ml)IL-17 (pg/ml)TNF-α (pg/ml)Chemerin (pg/ml)

Control
TNBS^^^^^^^^^
CE20
CE100###
LA10
LA50
SA
CE20+SA
CE100+SA###
LA10+SA
LA50+SA