Artichoke Polyphenols Sensitize Human Breast Cancer Cells to Chemotherapeutic Drugs via a ROS-Mediated Downregulation of Flap Endonuclease 1

Figure 2

MDA-MB231 proliferation in response to AEs/PTX cotreatment. Proliferation assay: cells were exposed to AEs (12.5-25 μM) plus and minus PTX (20 nM) for 24 h and the proliferation rate was measured by ³H-thymidine incorporation assay. PTX vs. 25 μM AEs+PTX . 25 μM AEs vs. 25 μM AEs+PTX .