Interleukin-6 Promotes Epithelial-Mesenchymal Transition and Cell Invasion through Integrin β6 Upregulation in Colorectal Cancer

Table 1

Association of IL-6 and integrin β6 expression with clinicopathological factors in CRC cases.

Clinicopathological factors		IL-6 expression			Integrin β6 expression
		Low	High		Negative	Positive
Gender				0.458			0.660
Male	83	40	43		49	34
Female	72	39	33		45	27
Age (years)				0.443			0.746
<60	66	36	30		41	25
≥60	89	43	46		53	36
Differentiation				0.009			<0.001
Well	53	35	18		41	12
Moderate	59	29	30		40	19
Poor	43	15	28		13	30
Tumor stage				0.013			0.083
T1-T2	91	54	37		50	41
T3-T4	64	25	39		44	20
N stage				<0.001			<0.001
N0	62	49	13		47	15
N1	58	21	37		35	23
N2	35	9	26		12	23
M stage				0.436			0.006
M0	132	69	63		86	46
M1	23	10	13		8	15
TNM stage				0.029			0.002
I-II	75	45	30		55	20
III-IV	80	34	46		39	41