Research Article
Water-Soluble Pristine C60 Fullerenes Inhibit Liver Fibrotic Alteration and Prevent Liver Cirrhosis in Rats
Table 2
Liver and plasma blood biochemical parameters for rats that experienced DEN+CCl4 fibrosis and cirrhosis and treated by C60FAS.
| Parameters | 10 weeks | 15 weeks | Control | Fibrosis | Fibrosis+C60FAS | Control | Cirrhosis | Cirrhosis+C60FAS |
| Bilirubin conjugated (μmol/l) | | | | | | | Bilirubin nonconjugated (μmol/l) | | | | | | | ALT (μmol/ml per h) | | | | | | | AST (μmol/ml per h) | | | | | | | ALP (μmol/ml per h) | | | | | | | LDH (U/l) | | | | | | | Urea (mmol/l) | | | | | | | Creatinine (μmol/l) | | | | | | | α-Amylase (g/l per h) | | | | | | | SOD (U/mg protein) | | | | | | | CAT (mol/mg protein) | | | | | | | GSH (nmol/mg protein) | | | | | | | GST (μmol/mg protein) | | | | | | | GP (nmol/mg protein) | | | | | | | MDA (μmol/mg protein) | | | | | | | PCG (μmol/mg protein) | | | | | | |
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compared to control; compared to the fibrosis/cirrhosis group. |