Differential Gender-Dependent Patterns of Cardiac Fibrosis and Fibroblast Phenotypes in Aging Mice

Figure 1

Left ventricular remodeling with age is differentially regulated within genders. (a-i): Representative histograms of heart and echocardiographic parameters in the young and aged mice groups of both sexes. HW: heart weight, BW: body weight, TL: tibia length, IVSTd: end diastolic interventricular septal thickness, LVIDd: end diastolic left ventricular internal diameter, LVPWd: end diastolic left ventricular posterior wall thickness, SV: stroke volume, EF: ejection fraction, FS: fractional shortening. animals per group. , and vs young male and female, , and vs aged female or male.

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