Ganoderic Acid D Protects Human Amniotic Mesenchymal Stem Cells against Oxidative Stress-Induced Senescence through the PERK/NRF2 Signaling Pathway
GA-D significantly reduced the generation of β-galactosidase. (a) The effect of different concentrations of GA-D on H2O2-induced premature senescence in hAMSCs by β-galactosidase staining; 0.1% DMSO group was used as a solvent control. . (b) Statistical analysis of SA-β-gal-positive cell rates. (c) Effect of different concentrations of GA-D on hAMSC viability through MTT assay. GA-D: ganoderic acid D. Data are presented as ,,#,##, vs. H2O2 group.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.