Ganoderic Acid D Protects Human Amniotic Mesenchymal Stem Cells against Oxidative Stress-Induced Senescence through the PERK/NRF2 Signaling Pathway
Pretreatment with GA-D could significantly prevent H2O2-induced premature senescence of hAMSCs. (a, b) Intracellular ROS levels were detected after pretreatment of GA-D. . (c, d) The influence of GA-D on H2O2-induced cell cycle distribution. (e–g) Relative expression of p21 and p16INK4a. (h) Production of telomerase. GA-D: ganoderic acid D. Data are presented as ,,,.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.