Research Article

Sitagliptin Mitigates Total Body Irradiation-Induced Hematopoietic Injury in Mice

Figure 1

Effects of sitagliptin on the survival of mice exposed to 7.5 Gy TBI. Mice were divided into 4 groups: the control group and 7.5 Gy group were intragastrically administrated with PBS, and the sitagliptin group and 7.5 Gy+sitagliptin group were intragastrically administrated with sitagliptin. The drugs were given for the first time 2 hours after the 7.5 Gy TBI, followed by continuous administration for 7 days, and the survival of the mice was observed for 30 days. Kaplan-Meier survival analysis of mice after TBI, , , .