Sitagliptin Mitigates Total Body Irradiation-Induced Hematopoietic Injury in Mice

Figure 3

Effects of sitagliptin on the functions of HSPCs. The grouping and administration methods are the same as above. BM cells were collected from mice 10 days after TBI. (a) BM cells were cultured in MethoCult GF M3534 methyl ligand medium, and the numbers of CFU-GMs were counted after 7 days. The proportion of donor cells in the recipient mice was measured 2 months after the donor cells were transplanted to the recipient mice; (b) Representative FACS analysis of the CRA; (c) The percentage of donor-derived cells in peripheral blood cells. Data were expressed as the (), .

(a)

(b)

(c)