Sitagliptin Mitigates Total Body Irradiation-Induced Hematopoietic Injury in Mice

<div>Effects of sitagliptin on the IR induced DNA injury of the hematopoietic cells. Grouping and administration methods as described above. Fixed and permeabilized BM cells after LSK antibodies incubation, then stained with <i>γ</i>H2AX phosphorylation antibody. (a) <i>γ</i>H2AX formation in BMMNCs; (b) <i>γ</i>H2AX formation in HPCs; (c) <i>γ</i>H2AX formation in HSCs. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Sitagliptin Mitigates Total Body Irradiation-Induced Hematopoietic Injury in Mice 