Protective Activities of Dendrobium huoshanense C. Z. Tang et S. J. Cheng Polysaccharide against High-Cholesterol Diet-Induced Atherosclerosis in Zebrafish

Figure 4

DHP improved LSS-induced EC dysfunction. (a) NO, (b) ET-1, and (c) PGI2 levels after EA.hy 926 cells were exposed to LSS by a parallel flow chamber with DHP (0.1, 1, and 10 mg/L) treatment or not. The mRNA expression of (d) eNOS, (e) ET-1, and (f) PGIS by RT-qPCR (). (g) The fluorescence intensity of NO after EA.hy 926 cells were exposed to LSS by a parallel flow chamber. SD was depicted as vertical bars. ^##, ^###, compared with the control group (LSS, 0 min); , , , compared with the LSS group (LSS, 30 min). Significance was calculated by one-way ANOVA followed by unpaired -test. represents the independent experiments.

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