TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways

<div>TBHQ alleviated the apoptosis induced by METH in the VTA. (a) Positive cells with a red fluorescence signal (arrows) were present in the VTA as determined by the TUNEL assay. (b) Quantitative statistical analysis of TUNEL-positive cells. A minimum of three random fields per group were used to count and calculate the percentage of positively labeled cells. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways 