TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways

<div>TBHQ increased the Nrf2 gene and protein immunocontent in the VAT of METH-induced rats. (a) Quantitative PCR analysis of VTA Nrf2 mRNA levels. (b) Representative Western blot images and analysis of HO-1. (c, d) Representative Western blot images and analysis of extranuclear and intranuclear Nrf2. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways 