Protective Effect of miR-204 on Doxorubicin-Induced Cardiomyocyte Injury via HMGB1

Figure 4

miR-204 inhibited inflammatory responses and apoptosis in mice treated with DOX. (a, b) Representative images and the quantitative analysis of CD45 and CD68 macrophages in the indicated groups (). (c) Representative images of TNF-α in each mouse heart (). (d, e) Representative images and quantitative TUNEL results (). (f, g) Western blot and quantitative analysis of apoptosis-related proteins in each group (). versus NS+GFP and ^# versus DOX+GFP.

(a)

(b)

(c)

(d)

(e)

(f)

(g)