β-Lapachone Increases Survival of Septic Mice by Regulating Inflammatory and Oxidative Response

Figure 2

β-Lap pretreatment increases septic mouse survival and stimulates mononuclear cell recruitment and phagocytosis. (a) The survival rate of septic mice from saline, β-Lap (50 mg/kg), and ceftriaxone (20 mg/kg) groups. (b) Body weight changes. (c) Leukocyte recruitment to infection site at 12 and 24 h post-CLP. (d) The phagocytic capacity of peritoneal cells 24 h after CLP. vs. sham; ^# vs. saline-CLP.

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