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Biofilm-producing strains | Quercetin/quercetin conjugate | Effect |
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Bacillus subtilis strain FB17 [41] | Quercetin | Quercetin diminished biofilm formation |
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Enterococcus faecalis MTCC 2729 [36] | Quercetin | At submic concentrations, quercetin inhibits biofilm formation. Compared with the control group, 10 and 9 proteins were overexpressed and effective after quercetin treatment |
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A vancomycin-resistant Enterococcus Faecalis [37] | Quercetin–pivaloxymethyl conjugate (Q-POM) | Q-POM efficiently hampered biofilm formation in a dose-dependent manner |
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Staphylococcus aureus ATCC 6538 [39] | Quercetin | Quercetin not only abolished the biofilm forming and hemolytic S. aura but also suppresses the expression of adhesion-related, quorum sensing, and virus-regulatory genes |
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Staphylococcus aureus ATCC 25923 [39] | Quercetin | Quercetin not only abolished the biofilm forming and hemolytic S. aura but also suppresses the expression of adhesion-related, quorum sensing, and virus-regulatory genes |
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A clinical isolate of Staphylococcus aureus [42] | Quercetin-AgNP hybrid | Quercetin-AgNP hybrid significantly reduced the formation of biofilms and the production of extracellular polymers |
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MSSA ATCC 29213, MRSA ATCC 33591, and clinical isolates of Staphylococcus aureus [43] | Quercetin | Quercetin (at MIC and sub-MICs) inhibited around 50% of biofilm establishment |
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Streptococcus mutans strain Ingbritt [44] | Quercetin-doped adhesive groups | Compared with the control group, the binder group doped with quercetin showed antibacterial activity, acceptable biocompatibility, inhibition of matrix metalloproteinases, and an effective bonding interfacial seal |
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Clinical isolates of Pseudomonas Aeruginosa [45] | Quercetin | Quercetin basically inhibits biofilm formation and twitching movements |
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Proteus mirabilis HI4320 [46] | Quercetin | Quercetin dose dependently increased biofilm establishment |
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Streptococcus pneumoniae strain D39 [47] | Quercetin | Quercetin reduced biofilm formation and CFUs in a dose-dependent manner |
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