Research Article

NAC Supplementation of Hyperglycemic Rats Prevents the Development of Insulin Resistance and Improves Antioxidant Status but Only Alleviates General and Salivary Gland Oxidative Stress

Table 2

Salivary gland function of rats.

CC+NACHFDHFD+NACANOVA

PG weight (mg)ab<0.0001
SMG weight (mg)a<0.0001
PG index0.41
SMG index0.07
TP PG (μg/mL)ab<0.0001
TP SMG (μg/mL)ab<0.0001
NWS flow (μL/min)0.077
SWS flow (μL/min)aa<0.0001

C: control group; HFD: high-fat-fed group; C+NAC: control rats+N-acetylcysteine supplementation; HFD+NAC: high-fat-fed rats+N-acetylcysteine supplementation; PG: parotid glands; SMG: submandibular glands; TP: total protein; NWS: nonstimulated whole salivary flow; SWS: stimulated whole salivary flow; a vs. C; b vs. HFD.