Olaquindox-Induced Liver Damage Involved the Crosstalk of Oxidative Stress and p53 In Vivo and In Vitro

<div>Depletion of p53 attenuated OLA-induced mitochondrial apoptosis pathway. (a, b) The expression of BAX and Bcl-2 was analyzed via immunohistochemistry. (c) Effects of p53 on OLA-induced ultrastructure changes in mouse liver observed by electron microscope (1200x). (d, e) Effects of p53 on OLA-induced activities of caspase 9 and caspase 3. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Olaquindox-Induced Liver Damage Involved the Crosstalk of Oxidative Stress and p53 In Vivo and In Vitro 