Ophiopogonin D Increases SERCA2a Interaction with Phospholamban by Promoting CYP2J3 Upregulation

Figure 12

Effect of OPD on CaMKII. OPD activated the phosphorylation of CaMKII in this ISO-induced HF cell model. By contrast, ox-CaMKII was altered very little. Oxidative CaMKII was activated by AngII, whereas OPD released the oxidation.