Research Article
Activation of the Melanocortin-1 Receptor by NDP-MSH Attenuates Oxidative Stress and Neuronal Apoptosis through PI3K/Akt/Nrf2 Pathway after Intracerebral Hemorrhage in Mice
Figure 4
Oxidative stress-related proteins were detected by ELISA at 24 h after ICH. (a–c) Administration of NDP-MSH at the dose of 5 and 15 μg/mouse markedly reduced the MDA level and increased CAT and SOD levels in the perihematomal brain tissue at 24 h after ICH. per group. # vs. sham group; vs. ICH + vehicle. MDA: malondialdehyde; CAT: catalase; SOD: superoxide dismutase.
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