The Effects of Alpha-Linolenic Acid on the Secretory Activity of Astrocytes and β Amyloid-Associated Neurodegeneration in Differentiated SH-SY5Y Cells: Alpha-Linolenic Acid Protects the SH-SY5Y cells against β Amyloid Toxicity

Figure 4

Effect of Amyloid β_1-42 (Aβ_1-42) treatment on differentiated SH-SY5Y cell viability. Aβ_1-42 treatment significantly inhibited the cell viability of differentiated SH-SY5Y cells in a dose-dependent manner as compared with the control. Differentiated SH-SY5Y cells (on the day 6th) were exposed for 24 h to Aβ_1-42 at different doses (5 μM, 10 μM, 25 μM, 40 μM). The obtained results are presented as a percentage of the control value. One-way ANOVA test for viability followed by Tukey’s multiple comparisons was used to analyse the data. Results are presented as (). Statistical differences between the treated and untreated control cells are indicated by asterisks ( for ; for ; for ).