Effect of Caesalpinia bonduc Polyphenol Extract on Alloxan-Induced Diabetic Rats in Attenuating Hyperglycemia by Upregulating Insulin Secretion and Inhibiting JNK Signaling Pathway
Table 8
Effect of CPP treatment on pancreatic antioxidant enzymes level in diabetic rats after 8 weeks.
Parameter
Normal
Positive control
250 mg/kg CPP extract
500 mg/kg CPP extract
Catalase (μmol/min/mg protein)
37 ± 1.9A
18.45 ± 1.02C
23.5 ± 1.27B
32.48 ± 2.2AB
GPx (nmol/min/mg protein)
17.5 ± 1.5A
9.5 ± 0.98C
12.38 ± 1.02B
15.87 ± 1.64AB
SOD (U/mg proteins)
4.1 ± 0.87A
2.4 ± 0.64C
3.05 ± 0.78B
3.8 ± 0.84AB
GSH (mg/dL tissue)
28.1 ± 0.9A
16.18 ± 1.04D
19.5 ± 0.86C
24.5 ± 1.3B
TBARS (nmol MDA/mg protein)
2.21 ± 1.04C
4.13 ± 1.01A
3.52 ± 0.87B
2.86 ± 0.79C
Data presented as . Values not having the same letters show significant difference within a column ().
