Research Article

Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts

Figure 5

PAC activated the Nrf2 pathway in osteoblasts. (a–d) Immunoblot showing Nrf2 and HO-1 levels in the differentially treated osteoblasts. (e) Representative fluorescence images showing Nrf2 localization in the differentially treated cells. Data are the of 3 independent experiments. , versus the untreated group, ## versus the Dex group.