Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts

<div>Mechanisms of the PAC action on GIOP. PAC reduces Dex-induced ROS accumulation and mitochondrial dysfunction in osteoblasts and prevents bone loss by activating the Nrf2 pathway.</div>

Oxidative Medicine and Cellular Longevity

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Figure 8

Figure 8: Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts 

Figure 8 | Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts 