Gentiopicroside, a Secoiridoid Glycoside from <i>Gentiana rigescens</i> Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress

<div>Effect of GPS on mitophagy in yeast. (a) Fluorescent images of YOM38 yeast containing plasmid pR316-GFP-Atg8 after treatment of GPS through MitoTracker Red CMXRos staining. (b) The percentage of YOM38 cells containing plasmid pR316-GFP-Atg8 with the colocation of autophagosome (green) and MitoTracker Red CMXRos (red). (c, d) The changes in ATG8-GFP, free GFP, and ubiquitin at the protein level in the mitochondria after treatment of GPS. Three pictures containing more than 60 cells in each group are used for statistical analysis.</div>

Oxidative Medicine and Cellular Longevity

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Figure 3: Gentiopicroside, a Secoiridoid Glycoside from <i>Gentiana rigescens</i> Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress 

Figure 3 | Gentiopicroside, a Secoiridoid Glycoside from Gentiana rigescens Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress 