Gentiopicroside, a Secoiridoid Glycoside from Gentiana rigescens Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress

Figure 5

Effect of GPS on the survival rate of yeast under oxidative stress condition and antioxidative enzyme activity in yeast. (a) Photograph of yeast growth after treatment of GPS under oxidative stress condition induced by H₂O₂ at 10.5 mM. (b) The survival rate changes in yeast under oxidative conditions at 5 mM H₂O₂. (c–f) The changes in CAT, T-SOD, SOD1, and GPx enzyme activities in yeast after treatment of GPS for 48 h. (g, h) Effect of GPS on ROS and MDA levels. Each experiment is repeated thrice. , , and indicate significant differences from the corresponding control (, , and ), respectively.

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